Transcranial echoscopy for diagnostic of Parkinson disease: technical constraints and possibilities
Keywords:
transcranial echoscopy, phased array transducer, hyperechogenicity, frequency range, acoustic window, amplitude aberration, phase aberration, dynamic focusing, defocusing effect.Abstract
Parkinson disease (PD) is one of the most common neurodegenerative disorders. The aim of this study is to review the main problems of transcranial echoscopy (TCE) by the pilot clinical investigations and to analyze opportunities and possible technical solutions for improvement of diagnostic of Parkinson disease using ultrasound applications. TCE is subjective enough yet, and strongly dependent on experience of physician.The suggestions for standardization of TCE are presented in this paper. The influence of temporal bone should be taken into account, because defocusing effects of the skull bone drastically decrease the quality of obtained brain images and these distortions are dependent on individual features of a subject.
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Published
2010-12-16
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APPLICATIONS IN BIOLOGY AND MEDICINE
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